注射用鹽酸氯普魯卡因具有明顯的鎮(zhèn)痛功效。
注射用鹽酸氯普魯卡因?qū)儆邗０奉惥致樗帲軌蜻x擇性地與神經(jīng)細胞膜上的電壓門控鈉離子通道受體結(jié)合，使鈉離子通道失活，從而阻礙快 Sodium channels on nerve cell membranes, inhibiting the fast sodium ion currents that underlie action potential generation and propagation. This effect is non-competitive and voltage-independent, meaning that it does not require depolarization of the membrane to occur. As a result, the neuron remains in its resting state and cannot generate an action potential, effectively blocking the conduction of nerve impulses.
因此，該藥物可以有效地阻斷神經(jīng)沖動的傳導，產(chǎn)生局部麻醉效果，達到鎮(zhèn)痛的目的。
在極少數(shù)情況下，使用注射用鹽酸氯普魯卡因可能會出現(xiàn)過敏反應、心血管抑制等不良事件。
使用注射用鹽酸氯普魯卡因時需密切監(jiān)測患者反應，并遵循醫(yī)師指導以確保安全有效的使用。如有不適或異常應立即告知醫(yī)生。
